The channel of death

نویسندگان

  • Alexei Degterev
  • Michael Boyce
  • Junying Yuan
چکیده

The proapoptotic members of the Bcl-2 family have been proposed to participate in the formation of a channel that releases these apoptogenic factors when mitochondria receive apoptotic signals. A recent study provides the first direct, biophysical measurement of a potentially apoptosis-specific mitochondrial channel, which is regulated by Bcl-2 family members and may play a primary role in the release of the proapoptotic factors.

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عنوان ژورنال:
  • The Journal of Cell Biology

دوره 155  شماره 

صفحات  -

تاریخ انتشار 2001